Facilities managers may come into contact with hazardous materials during maintenance activities, such as asbestos-containing materials, lead-based paints, or chemical cleaning agents. Without proper training and precautions, exposure to these substances can pose great health risks.

Working with electrical systems, wiring, and equipment exposes facilities managers to the risk of electric shock, burns, or arc flash incidents. Inadequate training, improper use of tools, or working on live electrical circuits can increase the likelihood of accidents and injuries.

Facilities managers working in environments with noisy equipment, HVAC systems, or construction activities may be at risk of noise-induced hearing loss or other auditory problems if adequate hearing protection is not used. In facilities such as hospitals, schools, or commercial buildings, facilities managers may encounter biological hazards such as mould, bacteria, or viruses. Poor indoor air quality or inadequate ventilation systems can contribute to respiratory infections, allergic reactions, or other health problems.